Ibuprofen-d4 is a deuterium-labeled Ibuprofen, a potent, orally active, selective COX-1 inhibitor with an IC50 value of 13 μM. It inhibits cell proliferation, angiogenesis, and induces cell apoptosis, functioning as a nonsteroidal anti-inflammatory agent and a nitric oxide (NO) donor. It can be used in the research of pain, swelling, inflammation, infection, immunology, and cancers.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuterium labeling has the potential to affect the pharmacokinetic and metabolic profiles of drugs